The AQUA project, aimed at enhancing resilience to climate change in the Adriatic-Ionian region, has the goal of reaching significant strides in addressing the common challenge of water management in the face of a changing climate. Rising temperatures, altered precipitation patterns, and extreme weather events have led to significant shifts in water availability, quality, and distribution. These challenges transcend borders and require collaborative efforts to ensure effective solutions. The AQUA project has set its sights on the overall objective of enhancing resilience to climate change of water utility companies in the Adriatic-Ionian area. By developing an joint action plan and strategy and user-tailored tools, the project aims to improve water resource management, increase capacities for climate change adaptation, and mitigate the impact of natural and man-made disasters. By adopting an integrated approach that considers both droughts and floods and the interconnections between water quantity and quality, the project aims to provide holistic solutions. The project also prioritizes data-driven solutions, co-design, and co-development, ensuring that the outputs are tailored to the specific needs of the participating regions.